FDA-Approved Treatment

Spravato for Depression

Spravato (esketamine) is an FDA-approved nasal spray that offers new hope for patients with treatment-resistant depression. Administered in our office with close clinical monitoring, it works rapidly — often when other treatments have not.

How It Works

A breakthrough for treatment-resistant depression

Spravato contains esketamine, a form of ketamine that targets the brain's NMDA receptors and glutamate system. This mechanism is fundamentally different from traditional antidepressants, which is why it can work when SSRIs, SNRIs, and other medications have not.

As the first FDA-approved treatment in a new class of antidepressants, Spravato represents a significant advance in psychiatric care — offering rapid relief and a new path forward for patients who have struggled to find effective treatment.

How SPRAVATO® works — a different mechanism from traditional antidepressants.

FDA-approved for treatment-resistant depression and MDD with suicidal ideation

Rapid onset — many patients experience improvement within days

Administered in-office under clinical supervision with a 2-hour monitoring period

May be covered by insurance — unlike IV ketamine infusions

Northern Lights Psychiatry Spravato treatment suite — private black leather recliners, lime-green pillows, purple abstract rug, and gold artwork
Spravato treatment suite

Our Facility

A calm, private space designed for your treatment

Spravato is administered in our dedicated treatment suite — a quiet, comfortable environment designed to support your experience. Each session takes place in a private recliner with access to headphones, soft lighting, and a calming atmosphere.

You will be monitored by our clinical team for the required two-hour observation period following each dose. Our goal is to make every session as comfortable and supportive as possible.

Who It Helps

Is Spravato right for you?

Spravato is FDA-approved for adults with specific diagnoses who have not responded adequately to prior antidepressant treatment. A comprehensive evaluation helps us determine if you meet the criteria.

Treatment-Resistant Depression (TRD)
Major Depressive Disorder (MDD)
MDD with Acute Suicidal Ideation or Behavior
Depression that has not responded to two or more antidepressants

REMS Program & Safety

Spravato is only available through a restricted distribution program called the Spravato REMS (Risk Evaluation and Mitigation Strategy). This means it can only be administered in certified healthcare settings — like ours — where patients are monitored for at least 2 hours after each dose.

Northern Lights Psychiatry is a certified Spravato treatment center. Our team is trained in the REMS program requirements to ensure your safety throughout every session.

Mark shares his experience with treatment-resistant depression and ongoing success with SPRAVATO®.

A Real Patient Story

Mark's story — finding hope after years of treatment-resistant depression

I have personally met Mark and listened to his story firsthand. What struck me most was not just the depth of what he had been through — years of trying medications that didn't work, the toll it took on his life and relationships — but the clarity and peace he carries today.

Mark is in ongoing, successful maintenance treatment with SPRAVATO®. He is not just surviving — he is living. His story is a powerful reminder that treatment-resistant depression does not have to be the end of the road.

"Stories like Mark's are why we offer SPRAVATO® at Northern Lights Psychiatry. When someone has tried everything and nothing has worked, they deserve access to something that might."

— Angela Peters, PMHNP-BC, Northern Lights Psychiatry

What to Expect

Your Spravato journey

01

Psychiatric Evaluation

We conduct a thorough evaluation to confirm a diagnosis of treatment-resistant depression or MDD with suicidal ideation and review your prior treatment history.

02

Insurance & Prior Authorization

Our team works with your insurance to obtain prior authorization for Spravato, which is covered by many plans when criteria are met.

03

In-Office Treatment Sessions

You self-administer the nasal spray under our supervision. You remain in our office for 2 hours after each dose for monitoring. You will need a driver home.

04

Ongoing Monitoring & Support

Spravato is used alongside an oral antidepressant. We monitor your response closely and adjust your overall care plan to support lasting improvement.

SPRAVATO® (esketamine) nasal spray — A different path forward for treatment-resistant depression in eligible adults. Learn More About SPRAVATO®.

SPRAVATO® (esketamine) is a prescription nasal spray for treatment-resistant depression in eligible adults. Visit spravato.com for full prescribing information, including Boxed Warning.

Patient Experiences

What our patients say

Real experiences from patients at Northern Lights Psychiatry.

5.0Google
"Angela Peters was so much better than the good I was expecting! She really listened and took everything I was saying to heart. We really scoped out exactly what was wrong and how we were going to go about helping me. She went above and beyond!"

Ashleigh N.

Verified
"Excellent experience! Angela Peters was very informative and ensured I got the help I needed. Highly recommended."

Patient

Verified
"She seemed to care more than most doctors I have dealt with in the past. Comfortability makes everything so much easier."

SL

Reviews sourced from Google. Individual results may vary.

Common Questions

Frequently asked questions

Take the Next Step

Find out if Spravato is right for you

Schedule a consultation with our team to discuss your history, prior treatments, and whether Spravato may be a good fit for your care plan.